Retiform Purpura Initially Concerning for Granulomatosis with Polyangiitis

This case appears in the HSS publication, Grand Rounds from HSS - Management of Complex Cases, Fall 2012 - Volume 3, Issue 3, Case 2

Case 2, described by two of our stellar rheumatology fellows, Danielle Ramsden-Stein, MD and Sonali Narain, MD, along with Michael D. Lockshin, MD, presents a woman who developed a dramatic necrotizing skin rash and numerous clinical and serologic manifestations that suggested a diagnosis of granulomatosis with polyangiitis. However, review of the skin biopsy with our pathologist revealed a classic picture consistent with an alternative diagnosis.

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