The Mineralized tissue Laboratory conducts studies on the mechanisms of biologic calcification in health and disease and on the changes that occur in mineralized tissues during development and aging. Research methods include cell culture, x-ray diffraction, FTIR spectroscopy, FTIR microspectroscopy and imaging and AFM-IR, micro-computed tomography, TEM and SEM, along with techniques of cell and molecular biology, histology, image analyses and solution chemistry.
Current investigations are focused on treatments for osteoporosis and osteogenesis imperfect. Specific questions being asked include: