February 04, 2011
Institutional Review Board, Hospital for Special Surgery
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We will examine the effects of platelet-rich-plasma (PRP) into regenerate bone following tibial osteotomy or unilateral deformity correction and we will compare it to a control group which will receive standard of care treatment. 62 patients will be included in this study; 31 of which will receive PRP injection and 31 which will receive standard of care treatment.
Inclusion:
• All patients enrolled must be between 30 and 60 years of age, inclusive.
• Patients with leg length discrepancy or bone loss equal to or less than 5 cm.
• Patients requiring a single level tibial osteotomy (unilateral or bilateral) followed by external fixation and undergoing distraction osteogenesis with regenerate 5mm to 50mm.
Exclusion:
• Patients greater than 60 or less than 30 years of age.
• Patients with leg length discrepancy or bone loss of greater than 5 cm.
• Significant metabolic bone disease (ex: Paget's, OI, Osteomalacia, etc)
• Tobacco smokers
Eugene Borst
BorstE@hss.edu
646.797.8249